The USP 43–NF 38 is the last edition that will be available in print or on a USB flash drive. Future supplements and editions – including the First and Second Supplements to USP 43–NF 38 – will not be printed or on flash drives. Starting with the First Supplement to USP 43–NF 38 that will be published on February 1, 2020, print and USB flash drive formats will not be available. Only the online format will contain all current USP–NF content.
USP is making these changes to align with the needs and expectations of our stakeholders and enhance support for regulatory compliance. Frequent updates to online systems ensure access to the most current information. Unlike the printed book and USB flash drive, which cannot be updated, the USP–NF Online platform is updated monthly to reflect the latest compendial content changes, including Accelerated Revisions that are posted monthly. In addition, the recent revision of General Notices emphasizes the goal of achieving a single source of official compendial content. These changes align with the transition to a fully electronic publishing model for USP publications and will also allow USP to target resources toward ongoing enhancements to the USP–NF Online.